Pulmonary Arterial Hypertension Market size was valued at USD 5.0 billion in 2015 and is anticipated to reach USD 8.7 billion by 2025. Pulmonary arterial hypertension (PAH) is a type of high blood pressure that occurs in the right side of the heart and in the arteries that supply blood to the lungs. These arteries are called pulmonary arteries. PAH occurs when the pulmonary arteries thicken or grow rigid. PAH is one of the five groups of pulmonary hypertension, classified by the World Health Organization (WHO).
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Market Synopsis of Pulmonary Arterial Hypertension Market:
Globally the PAH market is
segmented on the basis of Drug class, Surgery, and region. On the basis of Drug
class, the global PAH market is classified into Endothelin Receptor Antagonists
(ERAs) (Tracleer, Opsumit, Letairis)- These medications reverse the effect of
endothelin, a substance in the walls of blood vessels that causes them to
narrow; Prostacyclin and Prostacyclin Analogs- were the first medications
approved by the U.S. FDA for the treatment of PAH. Phosphodiesterase-5 (PDE-5)
V Inhibitors, Sildenafil, and Tadalafil- Revatio, Viagra, Cialis, etc. These
drugs work by opening the blood vessels in the lungs to allow blood to flow
easily. These drugs have superiority over existing therapy options with respect
to the therapeutic efficacy, route of administration, and side-effects.
A new drug called Uptravi
(selexipag), which is a selective IP prostacyclin receptor agonist, is expected
to be launched in 2016 and is likely to drive growth of the prostacyclin and
prostacyclin analogs market. The rising sales of these newly-approved
therapeutic agents are likely to contribute to the overall revenue of the
market.
Globally, regulatory bodies have
granted an Orphan Drug Designation (ODD) status to all those drugs intended to
diagnose and treat or cure a rare disease. In the U.S., the Orphan Drug Act
(ODA) encourages pharmaceutical industries to develop orphan drugs by offering
benefits such as tax credits, research grants, and orphan drug exclusivity of
seven years. These benefits are escalating the development, manufacturing, and
marketing of drugs intended to treat PAH, thereby driving market growth.
On the basis of surgeries, the
global PAH market is classified into Atrial Septostomy- This is an open heart surgery;
in which surgeon will create an opening between the upper left and right
chambers of your heart to relieve the pressure on the right side of heart.
Transplantation- Lung or heart-lung transplant might be an option especially
for younger people who have idiopathic pulmonary arterial hypertension.
Geographically, PAH market is
segmented into North America, Europe, Asia Pacific, Latin America, MEA, and
Rest of the World. North America held the maximum share of market for PAH in
terms of revenue in 2013, which is then followed by Europe. These two developed
regions are expected to witness substantial growth during the forecast period,
due to the recently approved PAH drugs in the market and the products that are
anticipated to receive approval during the next few years. In the Asia Pacific
region, Japan, China, India, Australia, and New Zealand exhibit immense
opportunities for the companies operating in the PAH market.
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Table of Contents:-
Chapter 1 Methodology and Scope
Chapter 2 Executive Summary
Chapter 3 Pulmonary Arterial
Hypertension: Market Variables, Trends & Scope
Chapter 4 Pulmonary Arterial
Hypertension: Product Estimates & Trend Analysis
Chapter 5 Pulmonary Arterial Hypertension:
Application Estimates & Trend Analysis
Chapter 6 Pulmonary Arterial
Hypertension: End-use Estimates & Trend Analysis
Chapter 7 Pulmonary Arterial
Hypertension: Industrial End-use Estimates & Trend Analysis
Chapter 8 Pulmonary Arterial
Hypertension: Regional Estimates & Trend Analysis
Chapter 9 Competitive Landscape
Chapter 10 Pulmonary Arterial
Hypertension: Manufacturers Company Profiles
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